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033 Metadarwinism & Hologenomic Evolution Dr Bill Miller

Metadarwinism: Evolution Via Microbial Cognition

Love & Communication vs. Survival & Death

As a physician, I noticed some aspects of disease dynamics that lead me to consider microbial cognition. That led, over time, to my interest in the hologenome, and an entire theory of evolution distinct from standard Darwinism that concentrates on the intersection of the hologenome, the microbiome, cognition, health and evolution.

~ William Miller

Metadarwinism Orientation: Molecular Science And Evolution

Just what is metadarwinism? Fasten your seat belts, then run to take out your dictionary… er, forget that dictionary. I initially told Dr. Miller that I would need some deeper resource, after reading his bio, to understand his remarks. However, he quickly reassured me/us with his engaging, humorous and entertaining commentary on this most interesting topic – cell talk and evolution.

Here Dr. Miller casually drops words beyond ordinary conversation, then interests all of us in the history of the communication efforts between cells, in the cognition of microorganisms, in the evolution of humankind.

Communication vs. Competition

Cell love has worked for millennia.

Natural starter links:

Cells Talk

Consider this concept: metadarwinism – it’s about reconsidering Darwin’s “survival of the fittest” as an old process that pales into insignificance when compared to the love that microbiota, those microorganisms – for example, our gut friends in the microbiome – have for each other. Consider how they get together over millennia to create… yes, us.

Dr. Miller is the author of The Microcosm Within: Evolution and Extinction in the Hologenome. A practicing physician for 30 years, now an independent researcher in evolutionary biology, a media commentator on health issues, the microbiome, and our evolution. And, he’s co-editor of the Society for the Advancement of Metadarwinism. Trust me; you will love this guy.

Relevant Metadarwinism Commentary

We have identified a mechanism that integrates development and physiologic homeostasis – cell-cell interactions. Why not apply that mechanism to Evolutionary Biology as the long-term basis for phylogenetic change? Using that approach at the cell-molecular level offers the opportunity to determine how cellular composition has accommodated adaptation. – Torday

When we think of evolution in terms of contemporary biologic phenotypes, we make the systematic error of reasoning backward from the present to the past. Yet reasoning after the fact, by definition, is illogical. All of biology is formed from and by cells, which emerged from the primordium 3-4 billion years ago, likely as primitive micelles formed from lipids. Such structures are semi-permeable, generating intracellular chemical gradients, a process referred to as chemiosmosis, ultimately allowing for the reduction of entropy within the cell, transiently circumventing the second Law of Thermodynamics. It was under these conditions that life began on Earth, initiated and perpetuated by the perennial competition between prokaryotes and eukaryotes, a battle which rages on to this day. – Torday

Darwin’s great success was in making the subject of evolution user-friendly by providing a narrative that was simple and direct. Pleasing as it may be, it is at best entirely incomplete. Think of it like the transition from Newtonian mechanics to relativity theory. As much is learned about the unicellular world with its surprising mechanisms and capacities, new pathways must be imagined. It is clear that we as humans are hologenomes, and all the other complex creatures are, too. In fact, there are no exceptions. – Torday & Miller

About Dr. Miller

“The most salient aspect of my experience that is pertinent to others is that a distinct passion arose without precedent in a field that was distinctly apart from the area of my training and expertise. It was completely unanticipated and not a response to any particular stimulus. It was indeed a chance to intersect with a prepared mind. From that point, it was one of compelling persistence against extremely formidable odds. I believe that many would be interested and inspired by my particular and very unusual path.”

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Dr. Miller’s Book & Additional References:

  1. The Microcosm Within: Evolution and Extinction in the Hologenome – Dr. Bill Miller
  2. Evolutionary Biology, Cell-Cell Communication, and Complex Disease – Drs. John Torday & Virender Rehan
  3. The Society For Metadarwinism
  4. Bio-Logic at Society For Metadarwinism – Dr. John Torday
  5. Man Is Integral With Nature – Drs. Torday and Miller


Complimentary 033 Miller Download Here:

Cognition, Information Fields and Hologenomic Entanglement:

Evolution in Light and Shadow

– Download Here –


Our Next CoreBrain Journal Episode

034: Dr. Bill Walsh – This is the second of three one-hour interviews with Dr. Walsh after his first on the controversial and yet clinically useful measurement and treatment for methylation issues . Over the past 30 years, Dr. Walsh has developed biochemical treatments for patients diagnosed with behavioral disorders, attention deficit (hyperactivity) disorder, autism, clinical depression, anxiety, bipolar disorders, schizophrenia, and Alzheimer’s disease that are used by doctors throughout the world. This second interview takes us into the often overlooked lands of Copper and Kryptopyrrole imbalances that directly contribute to high percentages of psychiatric treatment failure globally. Dr. Walsh reviewed over three million laboratory results, is widely published, presents at the American Psychiatric Association, and, to top it off, is a delightful, entertaining guest. Tune in for this deeper, essential next episode for Dr. Walsh’s molecular details that matter.


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